Proteomics & Bioinformatics in Drug Discovery
Proteomics, the large-scale analysis of proteins, contributes expressively to our understanding of gene function in the post-genomic era. Proteomics can be divided into three main areas: (1) protein micro-characterization for large-scale certification of proteins and their post-translational changes; (2) 'differential display' proteomics for comparison of protein levels with potential application in a extensive range of diseases; and (3) studies of protein–protein interactions using methods such as mass spectrometry or the yeast two-hybrid system. Proteomics technologies are under nonstop progresses and new skills are introduced. Nowadays high quantity acquisition of proteome data is possible.
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